Clinical microbiology of the dengue virus

Prevention is focused on reducing the adult mosquito populations, controlling mosquito larvae and protecting individuals from mosquito bites. Timing of specimen collection: For instance, the luminescence-based techniques are becoming increasingly popular owing to their high sensitivity, low background, wide dynamic range and relatively inexpensive instrumentation.

Haemagglutination-inhibition test The haemagglutination-inhibition HI test see Figure 4.

Specialist and reference microbiology: laboratory tests and services

However, it has a slightly higher sensitivity than the HI test. Human transmission of dengue is also known to occur after occupational exposure in healthcare settings e.

It must be emphasized, however, that because of the persistence of IgM antibody for 1 to 3 months, MAC-ELISA-positive results obtained with single serum samples are only provisional and do not necessarily mean that the dengue infection was current.

Between years there are often dramatic shifts in incidence rates. This area has been recently reviewed. The second clinical presentation occurs when a patient develops DF with or without hemorrhage.

Zika virus[ edit ] Symptoms vary on severity, from mild unnoticeable symptoms to more common symptoms like fever, rash, headache, achy muscle and joints, and conjunctivitis. MIAs can also be used to detect viruses. Additionally, climate impacts mosquito blood feeding patterns as well as extrinsic incubation periods.

These specimens will be further investigated by neutralization assays PRNT. Hemolysed, icteric, lipemic or microbially contaminated sera or plasma are not recommended for testing.

Dengue Disease

Since they do not produce any offspring, the population, and consequently the disease incidence, is reduced over time. The virus itself is composed of single-stranded RNA and has four serotypes.

Placing screens on windows and doors is a simple and effective means of reducing the number of mosquitoes indoors. After a second dengue virus infection, high-titre neutralizing antibodies are produced against at least two, and often all four, dengue viruses as well as against non-dengue flaviviruses.

The non-specific presentation of symptoms make positive diagnosis difficult based on physical exam and routine tests alone.Dengue fever is a mosquito-borne disease spread by Aedes aegypti mosquito.

Dengue fever is caused by dengue virus of genus Falvivirus. Dengue fever causes high fever, rash, and muscle and joint pain, bleeding, and hypotension. El dengue es una enfermedad infecciosa causada por el virus del dengue, del género flavivirus que es transmitida por mosquitos, principalmente por el Aedes willeyshandmadecandy.comn 4 tipos del virus de dengue.

La infección causa síntomas gripales, y en ocasiones evoluciona hasta convertirse en un cuadro potencialmente mortal, llamado dengue grave o dengue. Author Stats ℹ Author Stats: Publishing your article with us has many benefits, such as having access to a personal dashboard: citation and usage data on your publications in.

Clinical Dengue. Infection with any of the four dengue serotypes can produce the full spectrum of illness and severity.

The spectrum of illness can range from a mild, non-specific febrile syndrome to classic dengue fever (DF), to the severe forms of the disease, dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Furthermore, NS1 circulation in the bloodstream of patients during the clinical phase of the disease suggests a contribution of the nonstructural protein to dengue virus pathogenesis.

During flavivirus infection in vitro, nonstructural protein NS1 is released in a host-restricted fashion from infected mammalian cells but not vector-derived insect cells. This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies.

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Clinical microbiology of the dengue virus
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